The auction will feature: film memorabilia, including signed scripts, awards, props and clothing that relate to the careers of Marsha and Robin; contemporary art, including sculptures by Niki de Saint-Phalle and works by street artists including, Banksy, Shepard Fairey and Invader.
Plus, more than 40 watches from Robin's personal collection; a selection of bicycles and sports memorabilia and furniture and decorative art from their residences and more.
A portion of the proceeds from the auction will be donated to humanitarian organizations and institutions supported by Marsha and Robin, including The Juilliard School, Wounded Warrior Project, the Challenged Athletes Foundation, and the Christopher & Dana Reeve Foundation.
The sale will be preceded by an exhibition open to the public in the galleries of Sotheby's York Avenue from 29 September